AC-262536 (Accadine) is a compound which acts as a selective androgen
receptor modulator. Chemically it possesses endo-exo isomerism, with the endo
form being the active form. It acts as a partial agonist for the androgen
receptor with a Ki of 5nM, and no significant affinity for any other receptors
similarly to other SARMs because it interacts with androgen receptors in the
bones and muscles without affecting sexual tissue. The body’s androgen receptor
(AR) typically affects human sexual development, but once it has been activated
by compounds like testosterone it can affect other parts of the body like the
liver, muscles, bones and even the central nervous system.
The thing is that targeting AR signaling by
taking testosterone comes with side-effects that impact the sex tissues. This
means that in addition to developing strong bones and bigger muscles, you’ll
also have an increased prostate cancer risk and shrinking testicles.
Unlike other SARMs, AC-262,536 avoids this by
binding directly with the androgen receptor.
As a result, it activates the androgen
receptor specifically in the cells that make up your bones and muscles without
affecting sexual tissue or your liver enzymes.
AC-262536 is a promising new drug that’s
primarily aimed towards muscle growth. In comparison to testosterone,
AC-262,536 improved muscle growth at 66% the capacity of testosterone, but
without the negative side effects of steroid use.
AC-262536 can bind to androgen receptors and
suppress luteinizing hormone (LH) stronger than testosterone. AC-262536 can
improve muscle growth similarly to testosterone. At the same time, AC262536 does promote fat
loss by lowering your percentage body fat.
AC-262536 may have benefits for prostate
cancer as it can strongly antagonize the effects of dihydroxytestosterone (DHT)
in the human prostate cancer cell (in vitro).
Like the majority of SARMs, AC-262536 is safe
It doesn’t affect the body’s hormones, so it
proves to be a safe and efficient method of building muscle.
Serving size: 1 capsule
Servings per container: 30
Amount Per Serving
AC-262536 5 mg
Store at room temperature in a dry and cool place, out of reach of children.
Not to be consumed by children, pregnant and nursing women, people suﬀering
from liver or kidney diseases, and with allergies to any of the supplement